Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Research

BTDMJB. 2008; 4(1): 8-13

Restless legs syndrome in patients with hemodialysis

Hüseyin Atlı, Mehmet Çölbay, Serap Demir, Şeref Yüksel, İhsan Uslan, Gürcel Acartürk, Özcan Karaman, Tülay Köken, Mehmet Melek.

Objective: The restless legs syndrome (RLS) is characterized by unpleasant sensations and pain in the legs, irresistible urge to move the
legs, especially when resting and often accompanied by sleep disorders. RLS prevalence is up to 80% in hemodialysis patients. It is such an important clinical condition that is associated with increased mortality. Moreover etiopathogenesis is not clear. We aimed to evaluate vascular disorders, heart rate variability, oxidative stress parameter in hemodialysis patients with RLS.
Material and Methods: Study was conducted with hemodialysis patients. Twenty five patients diagnosed as RLS with International Restless Legs Study Group criteria, and twenty five patients without RLS (control group) were included to the study. Patients were examined with complete blood count and biochemical assays, Kt/V, oxidative stress parameter such as malon dialdehyde and sulphydryl, lower extremity Doppler ultrasonography and 24 hour holter heart rate variability.
Results: Patients with RLS had significantly lower hemoglobin and sodium levels (p:0.025 ve p:0.038). Tibialis posterior and anterior artery
şow was significantly reduced in patients with RLS (p:0.011 ve p:0.010). There was significant correlation about low hemoglobin and sodium level and reduced tibialis posterior and anterior artery şow. With logistic regression analysis, only hemoglobin was determined as independent factor on RLS (OR 6.211 [%95 CI 1.368-26.176] p=0.018).
Conclusion: It is concluded that hemoglobin is an important independent factor for progression to RLS. Therefore hemoglobin level must
be maintained in normal range especially in patients with RLS.

Key words: Restless legs syndrome, oxidative stress, heart rate variability, otonomic dysfunction, vascular disease

Article Language: Turkish English

Full-text options

Full-text Article

American Journal of Diagnostic Imaging


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.