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Original Research

Med Arch. 2013; 67(3): 181-184


Prolactinomas in Infertile Women: Clinical and Endocrine Characteristics Before and After 24 Months of Treatment with Bromocriptine

Midhat Hajder, Elmira Hajder, Melika Dervisefendic, Remzo Samardzic, Enisa Alic.




Abstract

Introduction: Prolactinomas are the most common tumors of the pituitary gland and cause of gonadal dysfunction and infertility. Objective: To determine the effects of bromcriptin to normalize prolactin, gonadal function more tumor mass and infertility. Patients and Methods: A prospective clinical study included 30 infertile women with micro-macro prolactinoma. We analyzed clinical parameters, the function of sex hormones, the maximum tumor diameter before and after 24-month therapy with bromocriptine. Results: Micro prolactinomas were significantly (66.3% vs. 33.7%, p

Key words: Prolactinomas, Gonadal dysfunction, Maximal tumor diameter, Bromocriptine.






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