Systemic lupus erythematosus (SLE) which is a chronic autoimmune disease can be presented with neuropsychiatric scenarios. Antibodies that react with neuronal antigens have been blamed in pathophysiology. In this article, current knowledge about the nervous system involvement of the SLE based on cases with epilepsy, polyneuropathy, plexitis, and cerebral vasculitis was reviwed.
Key words: SLE, neuropsychiatric, epilepsy, neuropathy, vasculitis.
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