Background: Since the March of 2020, when the first case of SARS-CoV-2 infection was reported in our country all efforts of medical staff were focused on diagnosing and treatment of patients that developed COVID-19 disease. Objective: This study aimed to determine frequency of headaches in SARS-CoV-2 infected patients in Canton Sarajevo during 2020. Methods: A retrospective observational study involved 155 participants with COVID 19 infection in 2020 older than 18 year. A detailed analysis of such headache was done through on line survey (Google form). All participants were well informed about the research and they all signed up informed consent. Results: From total 155 patients that were included in this study 128 were female (82.6%) and 27 were male (17.4%). The most participants (36.8%) were in the age range of 31-44 years. Headache (49%), after the fever (59%) and body aches (51,6%), was one of the most frequent first symptom of SARS-CoV-2 infection. Headache experienced 134 (86,5%) patients, 115 (89,8 %) female and 19 (70,4%) male. In 27,7% cases headache was moderately severe. According to time period that had past from first symptoms, including headache, to positive result of PCR test, 122 (78,7%) patients had headache 1-5 days, 32 (20,6%) patients had headache 6-10 days, 6 (3,8%) patients had 10-15 days and 5 (3,22%) patients had headache more than 15 days before testing. Conclusion: Headache is one of the most frequent symptoms of SARS-CoV-2 infection. Is often an early warning of COVID-19 infection. Even though headaches are a less well-known symptom of COVID-19, they are one of the earliest signs of the disease and more common than the symptoms of cough, fever and loss of smell.
Key words: headache, COVID-19, SARS-CoV-2 infection