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Original Research

RMJ. 2019; 44(4): 694-697


Association of thyroid and bleeding disorder with menstrual irregularities in teenage girls in a tertiary care hospital.

Nadia Ahmad Bokhari, Ruqia Begum, Wardah Ajaz Qazi, Samina Irshad, Asia Raza, Ambreen Fatima.

Abstract
Objective: To determine the association of thyroid and bleeding disorder with menstrual irregularities in teenage girls in a tertiary care hospital.
Methodology: This cross-sectional descriptive study was conducted in department of obstetrics and gynecology, Fauji Foundation Hospital from September 2017 to September 2018 and included 102 unmarried girls from menarche to 19 years of age with menstrual irregularities. They were selected by non-probability convenience sampling. Details of menstrual cycle including pattern of bleeding, blood loss, symptoms of thyroid disorders, personal and family history of bleeding disorders, clinical examination and investigations were recorded.
Results: Out of 102 females, 16 (15.6%) had thyroid dysfunction with hypothyroidism in 13(12.7%) and hyperthyroidism in 3(2.9%). In the females with clinical hypothyroidism, 9.8% had heavy menstrual bleeding while 2% had polymenorrhea and 7.7% had hypomenorrhea. In those with hyperthyroidism, hypomenorrhea was found in 2%, while heavy menstrual bleeding in 1%. Regarding the underlying cause of heavy menstrual bleeding in 102 patients, 10(9.8%) had bleeding disorders as the underlying cause, 8(7.8%) has Von Willebrandís disease and idiopathic thrombocytopenia was found in 2(1.9%) females.
Conclusion: Thyroid disorders are an underdiagnosed but curable cause of menstrual irregularities in young teen age girls. Both hypothyroidism and hyperthyroidism can depress ovarian and menstrual function. Bleeding disorders is rare and important cause of heavy menstrual bleeding in young girls. Therefore, a detailed history, examination and investigation including thyroid function test and clotting profile should be done in in all the young teenage girls presenting with menstrual irrerugalritis.

Key words: Abnormal Uterine Bleeding (AUB), bleeding disorders, heavy menstrual bleeding (HMB), hypomenorrhea, polymenorrhea.






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