We report the case of a 23-year-old man with bipolar disorder who developed permanent cerebellar damage of lithium intake within therapeutic ranges. Cerebellar symptoms such as dysarthria, ataxia, and tremor developed 1 year after the beginning of lithium. Two years later, cerebellar signs and symptoms were found to be permanent in the patient. Cerebellar syndrome was most probably due to lithium neurotoxicity, which was associated with the administration of antipsychotic.
Key words: lithium, Cerebellar syndrome, permanent neurotoxicity
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