The aim of the study was detection of diastolic dysfunction of myocardium with Tissue Doppler Imaging (TDI) in asymptomatic type 2 diabetic patients, in five years duration of disease, and normal cardiac function on conventional echocardiography (CE), according to the performance showed on exercise stress test. Material and Methods: We studied 300 patients, of them 150 patients with non-obese, normotensive, uncomplicated type 2 diabetes, in five years duration of disease and 150 healthy control subjects. Of all patients, 100 with type 2 diabetes, and 100 patients from the control group underwent exercise test on a treadmill. All participants underwent both CE and TDI echocardiography. With TDI, lateral E peak velocity, atrial velocity (A), their ratio (E/A) and systolic velocity (S) were measured. Diastolic dysfunction was diagnosed by tissue Doppler imaging, and the following criterion was met: E/A ratio
Key words: echocardiography, diabetes mellitus, diastolic dysfunction, tissue Doppler imaging.