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Left Ventricular Diastolic Dysfunction in Asymptomatic Type 2 Diabetic Patients: Detection and Evaluation by Tissue Doppler Imaging

Bedri Faik Zahiti, Daut Rashit Gorani, Fitim Bejtullah Gashi, Sami Bajram Gjoka, Lorita Bedri Zahiti, Bekim Sylë Haxhiu, Lulzim Selim Kamberi.




Abstract

The aim of the study was detection of diastolic dysfunction of myocardium with Tissue Doppler Imaging (TDI) in asymptomatic type 2 diabetic patients, in five years duration of disease, and normal cardiac function on conventional echocardiography (CE), according to the performance showed on exercise stress test. Material and Methods: We studied 300 patients, of them 150 patients with non-obese, normotensive, uncomplicated type 2 diabetes, in five years duration of disease and 150 healthy control subjects. Of all patients, 100 with type 2 diabetes, and 100 patients from the control group underwent exercise test on a treadmill. All participants underwent both CE and TDI echocardiography. With TDI, lateral E’ peak velocity, atrial velocity (A’), their ratio (E’/A’) and systolic velocity (S’) were measured. Diastolic dysfunction was diagnosed by tissue Doppler imaging, and the following criterion was met: E’/A’ ratio

Key words: echocardiography, diabetes mellitus, diastolic dysfunction, tissue Doppler imaging.






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