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Left Ventricular Diastolic Dysfunction in Asymptomatic Type 2 Diabetic Patients: Detection and Evaluation by Tissue Doppler Imaging

Bedri Faik Zahiti, Daut Rashit Gorani, Fitim Bejtullah Gashi, Sami Bajram Gjoka, Lorita Bedri Zahiti, Bekim Sylë Haxhiu, Lulzim Selim Kamberi.

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The aim of the study was detection of diastolic dysfunction of myocardium with Tissue Doppler Imaging (TDI) in asymptomatic type 2 diabetic patients, in five years duration of disease, and normal cardiac function on conventional echocardiography (CE), according to the performance showed on exercise stress test. Material and Methods: We studied 300 patients, of them 150 patients with non-obese, normotensive, uncomplicated type 2 diabetes, in five years duration of disease and 150 healthy control subjects. Of all patients, 100 with type 2 diabetes, and 100 patients from the control group underwent exercise test on a treadmill. All participants underwent both CE and TDI echocardiography. With TDI, lateral E’ peak velocity, atrial velocity (A’), their ratio (E’/A’) and systolic velocity (S’) were measured. Diastolic dysfunction was diagnosed by tissue Doppler imaging, and the following criterion was met: E’/A’ ratio

Key words: echocardiography, diabetes mellitus, diastolic dysfunction, tissue Doppler imaging.

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