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A study of correlation between body mass index and lipid profile in postmenopausal women

Sunita Shailendra Ingale, Anupriya A Deshpande.


Abstract

Background: Menopause is a physiological event in every woman’s life which is characterized by cessation of menses due to hormonal changes. Menopause occurs between the late 40s and early 50s. Postmenopausal women are particularly at risk of cardiovascular complications due to loss of protective effect of estrogen on cardiovascular system. During menopause, there is fall in estrogen and progesterone levels. After menopause, there is increase in fat storage with simultaneous lipid deposition in central part of body. The body mass index (BMI) has a major influence on blood pressure and lipid profile and as such is a good predictor of hypertension and hyperlipidemia. Menopause predisposes the woman to the risk of ischemic heart disease.

Aims and Objectives: This study was carried out to correlate between BMI and blood triglyceride level and low-density lipoprotein (LDL) in postmenopausal women. These parameters were studied in 100 postmenopausal apparently healthy women.

Materials and Methods: Our study was approved by the institutional ethics committee. The subjects were divided into two groups according to the duration of their menopause period 5 years. Parameters studied were BMI and triglycerides and LDL.

Results: In our study in both groups, BMI values were raised but statistically not significant (P = 0.920), and in lipid profile, triglycerides (P = 0.059) and LDL cholesterol were raised and were statistically significant (P = 0.307).

Conclusion: Since postmenopausal women lack cardioprotective action of estrogen, they are prone to cardiovascular diseases faulty habits of diet and lifestyle further increase the risk of cardiovascular disease. Awareness among perimenopausal women about menopause and cardiovascular health should be created and women are encouraged to adapt healthy life.

Key words: Postmenopause; Estrogen; Lipid Profile; Body Mass Index






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