Background: Myopia is a common condition affecting a significant proportion of the pediatric population in Asian countries.
Aim and Objectives: This study was undertaken to investigate the associations of optical coherence tomography measurements of macular volume and macular thickness with refractive error and axial length in Indian children.
Materials and Methods: The prospective observational study was carried out at MRA Medical College, Ambedkar Nagar, Uttar Pradesh. We enrolled 300 consecutive cases (190 cases and 110 controls) of pediatric age group (6–18 years) between January 2015 and December 2018. Pearson’s correlation was performed with refractive errors, axial length, macular thickness, and volume.
Results: Children with myopia (SE −0.5–−4.57 D) tended to have smaller total macular volume and thinner macular thickness as, compared to control. The correlation of macular thickness and macular volume was analyzed with spherical equivalent (SE) and axial length. Macular thickness had negative correlation with SE and positive with axial length, correlation coefficients being observed as (r = −0.886 and 0.880, P ≤ 0.001). Total macular volume correlated negatively with SE, (r= −0.771, P ≤0.001) and positively with axial length (r = 0.764, P ≤0.001).
Conclusion: Increasing axial myopia was associated with increased macular volume and thickness. It establishes the importance of the fact that refractive error should be considered in the interpretation of macular thickness.
Key words: Myopia; Spectral-Domain Optical Coherence Tomography; Indian Children, Macular Thickness, Axial Length
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