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Review Article

NMJ. 2021; 10(2): 31-35


Evolving paradigm in drug resistant epilepsy radiosurgery - Techniques, indications and outcomes

Shankar Vangipuram, Muthukani S.




Abstract

Drug resistant epilepsy is one of the most common chronic neurologic disorders. These patients are at increased risk for serious morbidity and mortality, including cognitive disorders, poor academic performance, unemployment, depression, physical trauma, and sudden death in epilepsy. The goals of treatment for individuals with drug-resistant epilepsy are to render the patient seizure free, avoid treatment-related adverse effects, and allow the individual to become a participating and productive member of society. Focal cortical resection is a consideration in patients with drug-resistant focal epilepsy if the seizures emanate from a region that can be removed with minimal risk of disabling neurologic or cognitive dysfunction. Concerns regarding surgical morbidity especially on the cognitive function, visual field deficits limiting to superior quadrant, psychiatric problems have generated enthusiasm for more minimally invasive interventions like Stereotactic Radiosurgery (SRS) , Laser Interstitial thermal therapy (LIIT), Radiofrequency thermocoagulation & Focussed ultrasound.Authors in this article discussed the technque, indications and complications of SRS for drug resistant epilepsy.

Key words: cyberknife, cavernoma, corpus callosotomy drug resistant epilepsy, gammaknife, hypothalamic hamartoma, mesial temporal sclerosis, radiosurgery






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