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Original Research

Nig. J. Basic Appl. Sci.. 2012; 20(4): 297-304


Effects of Vitamin C on Kidney and Bone of Rats Exposed to Low Doses of Cadmium

AA Omonkhua, FO Obi.




Abstract

In this study, the effect of vitamin C on cadmium-induced toxicity was investigated. Wister rats were exposed to cadmium (as CdSO4.8H2O), by sub-cutaneous injection, at doses of 1.0, 2.0 and 3.0 ìg/kg body weight, with or without vitamin C supplementation, for four weeks. Serum alkaline phosphatase activity of the group of rats not supplemented vitamin C (group III) significantly (p

Key words: Cadmium, Vitamin C, Toxicity, Kidney, Bone






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