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J Complement Med Res. 2016; 5(4): 451-458

Congenital Malformations in Fetal Andearly Neonatal Autopsies in a Tertiarycare Hospital

Pradnya P. Kale, Sujata R. Kanetkar, N. S. Kshirsagar, Pramod Shah.

The awareness regarding fetal and neonatal (perinatal) mortality and its preventable causes is increasing. It has led to increase in finding the preventable causes of death in perinatal period. Out of 223 perinatal autopsies performed 57 (25.56%) had congenital Malformations. On comparing the sex ratio, the congenital malformations were slightly more in males (52.63%) with male to female ratio being 1.25:1. In the present study, there were 3 cases (5.26%) where sex of the fetus was ambiguous. Most congenital fetuses ranged from 20 to 24 weeks (63.15%) of their gestational ages. This could be attributed to therapeutic termination done in this period after detecting malformation on Ultrasonography. In this study the 13/57 (22.80%) cases showed multiple malformations occurring in single fetus or neonate. Variety of syndromes have been identified in the study like Down‘s syndrome, Potter‘s syndrome etc.

Key words: Down’s syndrome, neonatal, malformations

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