Thiazoles are important five-membered heterocyclic ring due to their broad spectrum of activities. The aim of the study, to summarize the medicinal effects and current approaches adopted for the synthesis of the thiazole and thiazole derivatives using different aspects. The medicinal significance of the thiazoles such as antibiotics, antimicrobials, antineoplastic, anti-inflammatory, diuretics and anti-thyroids. These routes are classified semisynthetic, synthetic or natural products for thiazole derivatives.
Key words: Thiazoles, antibiotics, antimicrobials, semisynthetic, natural products.