Abstract

Although general pediatricians play a key role in the early recognition of cystic fibrosis and timely referrals, real-world data on cystic fibrosis-related knowledge and practice patterns are limited in settings with nationwide newborn screening. This study aimed to evaluate general pediatricians' knowledge, awareness, and clinical practices related to cystic fibrosis, and to identify potential gaps that may affect early diagnosis and management. We conducted a cross-sectional, questionnaire-based online survey of general pediatricians actively practicing in Türkiye (November–December 2025). The survey included demographics, a 13-item cystic fibrosis knowledge assessment (score range 0–13), clinical practice items (reported descriptively), and education/training needs. A total of 412 pediatricians were included (mean age 37.81±5.63 years; 54.1% female). The mean knowledge score was 10.11±1.32. Clinically relevant uncertainty was observed for newborn screening interpretation: 35.0% selected “not sure” for the statement “cystic fibrosis cannot be present if newborn screening is negative.” Referral frequency for suspected cystic fibrosis was low (frequently 1.5%, rarely 88.3%, never 10.2%). Self-perceived adequacy in diagnosing/referring suspected CF was moderate (2.94±0.82) and strongly correlated with knowledge score (r=0.647, p

Key words: Cystic fibrosis, medical education, knowledge assessmen