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AJVS. 2022; 73(2): 56-64

Eggshell Membrane Repurposing from the Perspective of Tissue Engineering: A Non-Systematic Review

Hoda Elkhenany, Nermeen Eldebany, Eman Said, Asmaa Elsayed, Maria George, Mostafa Gamal, Mahmoud El-Kammar, Ramadan Abdel-Wahed, Ahmed Korittum, Howaida Abu-Ahmed, Samir Nouh, Mostafa Kassem, Sara Ali, Samy Khalil.


Natural resources are rich in collagen and growth factors that can perfectly fit in tissue engineering and contribute to the extracellular matrix of many tissues. The thin membrane that coats the inner surface of the eggshell is one of these resources that meets the need of tissue engineering as it contains high collagen, growth factors, and glycosaminoglycans. With advanced technology, eggshell membrane (EgS-M) has been available in many forms like powder, solution, and thin sheets for broad applications. Furthermore, integrating nanoparticles has provided a broad-spectrum EgS-M biomaterial with antimicrobial, anti-inflammatory, biocompatible, and biodegradable properties. Herein, we discuss the current status of EgS-M's contribution to tissue engineering of skin, cartilage, bone, periodontal, myocardium, and nerve.

Key words: Biomaterials, Regenerative medicine, Eggshell membrane, Eggshell membrane powder

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