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Role of serum HsCRP as prognostic markers in septicemia in elderly population

Arvind Anand, Nilesh Kumar, Indrajeet Singh Gambhir, Dhiraj Kishore, Ankur Nandan Varshney, Ashutosh Tiwari.


Background: Presence of elevated serum HsCRP is strongly associated with morbidity and mortality in diverse populations with sepsis and is a potentially useful biomarker to risk stratify patients with severe sepsis.

Aims & Objective: We aimed to study whether the serum HsCRP level at presentation in elderly patients with sepsis correlate with stage of sepsis and ultimate outcome.

Material and Methods: In a single centre prospective, observational study conducted in geriatric ward of tertiary care centre, 200 elderly patients (age>60 yrs) with sepsis were included. The primary outcome was 14 days in hospital mortality. Risk factor variable was venous serum HsCRP (mg/l) at presentation.

Results: Mortality at 14 days in elderly patients with sepsis was 20%. Mean serum HsCRP in survivor group was 33.42 ± 21.56 while 57.28 ± 25.31 in mortality group (p value

Key words: HsCRP, Acute Phase Reactant, Infection, Sepsis,elderly

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