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RMJ. 2013; 38(2): 188-189


Autoimmunity under the umbrella of “Danger Model”: new insights into tolerance, rejection and autoimmune therapeutics

Muhammad Asif Qureshi.

Abstract
This perspective article highlights the importance and relevance of Matzinger’s danger model in understanding, investigating and designing new therapies for autoimmune disorders. The take home message is to address the root causes that elicit the immune response rather than barricading the latter.

Key words: AutoImmunity, Danger Model, Tolerance



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