Background: In patients with osteoarthritis having knee and hip arthroplasty, the incidence of preoperatively elevated serum inflammatory markers was assessed, as well as their relationship to periprosthetic joint infection (PJI). The study also assessed how preoperative and postoperative factors related to a protracted postoperative hospital stay affected outcomes. Methodology: Patients who received primary hip and knee arthroplasty were included in the study. Patients who had open wounds, polytrauma involving other systems, or who had received an intra-articular steroid injection within the three months before to surgery were excluded. Anti-inflammatory indicators were identified during the preoperative assessment. All essential information was retroactively gathered and recorded. Results: 50 patients, with a male to female ratio of 0.624 and a mean age of 59.8±10.8 years, participated in the study. 68% of patients had one or more comorbid conditions before surgery. In 26.61% of patients, high preoperative levels of CRP and/or ESR were discovered. 3.84 percent of individuals experienced PJI and recovered after treatment. The average length of stay for patients was 13.37±5.75 days. There were no more issues found. Conclusion: High preoperative ESR and CRP were not associated with an increased risk of PJI. However, it was shown that factors such as preoperative NLR, alkaline phosphatase, haemoglobin, and the type of operation were useful in determining how long a patient would need to stay in the hospital after surgery.
Key words: total knee arthroplasty, osteoarthritis, erythrocyte sedimentation rate, NLR C-reactive protein, periprosthetic joint infection
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