Antimicrobial drug resistance is a major problem in worldwide, because the resistance microbial pathogens are emerged due to its genetic plasticity. Over usage of inappropriate antibiotics has become the prominent factor for the emergence of multidrug resistant (MDR). From the ancient time itself, plants are used as a principal source for medicinal agent/ drugs, which are lesser side effect compared to the commercially available synthetic drugs. The usage of traditional medicines and its related medicinal plants are helps to lead a healthy life. Here, we use two medicinal valuable plants like Cyclea peltata and Tiliocora acuminatato determine the antimicrobial resistance capacity using various solvents. In this water extracts were not revealed that much of inhibition against human pathogens when compared with other solvents such as, C. peltata showed maximum zone of inhibition against B. subtilis (chloroform) and E.coli (ethanol), whereas for using T. acuminate showed better activity against E. coli, S. pyogenes (ethanol) and K. pneumoniae, P. aeruginosa and S. aureus (chloroform).
Key words: Antibiotics, multidrug resistant, traditional plants, herbal medicine and inhibition
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