Hypertension and Hypercholesterolemia are a major public health problem in the developed Countries recently. Hypertension and hypercholesterolemia are frequently treated with antihypertensive drugs like calcium-channel blockers, angiotensin-converting enzyme inhibitors, and angiotensinII (AT1) receptor blockers, and statins. Irbesartan is angiotensin II receptor type 1 antagonist and widely used in treatment of hypertension condition. Atorvastatin is HMG CoA reductase inhibitor and widely used in treatment of hyper lipidaemias condition. .Combination of irbesartan and atorvastatin is used in the treatment of cardiovascular diseases like hypertension and hyper lipidemias. So this combination therapy gives antihypertensive and antilipidemic effects in the treatment of coronary artery diseases.
Irbesartan, Atorvastatin, Antihypertensive, Antilipidemic, Pharmacology, Combination Therapy.