Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Review Article

JCR. 2014; 1(1): 1-9


DIFFERENT CHEMICAL, BIOLOGICAL AND MOLECULAR APPROACHES FOR ANTI-HYPERLIPIDEMIC THERAPY WITH SPECIAL EMPHASIS ON ANTI-HYPERLIPIDEMIC AGENTS OF NATURAL ORIGIN

ASHOK K SINGH, VINEY CHAWLA, SHAILENDRA K SARAF, AMIT KUMAR KESHARI.

Abstract
Elevated levels of serum cholesterol leading to atherosclerosis can cause enhanced risk factors for coronary artery diseases (CAD). Reduction in serum cholesterol levels reduces the risk of CAD, substantially. Medicinal chemists all around the world have been designing, synthesizing, and evaluating a variety of new bioactive molecules for lowering lipid levels. Even so, some patients in the high risk category fail to achieve recommended cholesterol levels and to bring about regression of the already existing atherosclerotic lesions with currently available medications. Thereby, development of novel approaches to battle the world epidemics of hyperlipidemia remains relevant. In addition to existing treatments, some other recent chemical, biological and molecular approaches for the development of novel antihyperlipidemics are discussed herein. But none of these approaches are currently approved for use in humans. Several ongoing agents are in their different stages of clinical trials, in expectation of promising antihyperlipidemic drugs.

Key words: Antihyperlipidemia, Atherosclerosis, Coronary heart diseases (CHD), Statins and Nonstatins.



Similar Articles

New benzyltriethylammonium/urea deep eutectic solvent: Quantum calculation and application to hyrdoxylethylcellulose modification.
Azougagh O, Essayeh S, Achalhi N, El Idrissi A, Amhamdi H, Loutou M, El Ouardi Y, Salhi A, Abou-Salama M, El Barkany S
Carbohydrate polymers. 2022; 276(): 118737

Passive social media use and psychological well-being during the COVID-19 pandemic: The role of social comparison and emotion regulation.
Yue Z, Zhang R, Xiao J
Computers in human behavior. 2022; 127(): 107050

Carbonaceous materials for removal and recovery of phosphate species: Limitations, successes and future improvement.
Recepoglu YK, Goren AY, Orooji Y, Khataee A
Chemosphere. 2022; 287(Pt 2): 132177

A Transfer Learning-Based Approach with Deep CNN for COVID-19- and Pneumonia-Affected Chest X-ray Image Classification.
Chakraborty S, Paul S, Hasan KMA
SN computer science. 2022; 3(1): 17

Biovalue in Human Brain Banking: Applications and Challenges for Research in Neurodegenerative Diseases.
Vedam-Mai V
Methods in molecular biology (Clifton, N.J.). 2022; 2389(): 209-220


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites