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Review Article

JCR. 2016; 3(3): 50-55


IONIC LIQUIDS AS SOLVENTS AND CATALYSTS FOR THE GREEN SYNTHESIS OF COUMARINS

ELENI KAVETSOU, ANASTASIA DETSI.

Abstract
Coumarins have a wide variety of applications in the fields of pharmaceuticals, cosmetics and food additives. Therefore, the development of mild,
efficient, and eco-friendly benign synthetic methodology is necessary. Ionic liquids (ILs) are environmentally friendly with green chemistry
credentials and can be regarded as greener alternatives for conventional organic solvents. The present review focuses on the synthetic approaches
toward coumarin analogues that use ILs as a solvent and/or as a catalyst. The review includes the literature after 2005, with the exception of some
important historical articles on coumarin derivatives.

Key words: Coumarins, Ionic liquids, Pechmann reaction, Knoevenagel reaction, Microwave irradiation, Green synthesis



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