Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Review Article

JCR. 2019; 6(3): 7-13


A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION

MANASVI BOMMAREDDY, SHRIPAD HEBBAR.

Abstract
One of the major problems in obstetrics and neonatology till today is the occurrence of preterm births in spite of best possible antenatal care. Many
preterm labour are due to PPROM (Prelabour Preterm Rupture of Membranes) where infection plays a major role. The neonatal morbidity and
mortality is directly related to maternal infection and early-onset neonatal sepsis. Laboratory evaluation of various inflammatory markers such as
TLC (total leucocyte count), ESR (Erythrocyte Sedimentation Rate), CRP (C-Reactive Protein) predict events such as maternal chorioamnionitis,
neonatal sepsis with reasonable accuracy and hence are valuable tools in high dependency obstetric (HDU) and neonatal intensive care units
(NICU). The following treatise mainly focusses on aetiopathogenesis, clinical features, haematological and biochemical parameters of maternal
PPROM and neonatal sepsis. Understanding these factors will definitely prevent adverse maternal outcomes such as postpartum infections and
puerperal sepsis and perinatal events such as stillbirth due to intrauterine foetal infection, preterm birth, neonatal sepsis, long term sequele of
chronic lung disease and brain injury leading to cerebral palsy and other neurodevelopmental disabilities.

Key words: PPROM, EONI, Chorioamnionitis, C Reactive Protein, Neonatal sepsis



Full-text options

Full-text Article




Advertisement
American Journal of Preventive Medicine and Public Health

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.