Erythema Multiforme is an Acute Mucocutaneous disorder which is characterised by Ulceration, Erosions & bleeding then blistering of cutaneous lesions over the body. In this case study a 35 years old male patient had multiple erythematous papulus over the retroauricular regions which evolved into vesicles & coarse to form erythematous plaques over the upper limb, lower limb, Abdomen, chest, back & genitals and also vesicles developed over the lips which rupture to form crusts. This episode was mainly related to repeat drug intake of NSAIDs with different classes (Propionates & Arrylacetates) & doses for a chest pain as a daily regimen excisional biopsy of ruptured lesions was performed; the diagnosis was confirmed as Erythema Multiforme major. The patient was treated with Antibiotics & steroids in a tapering dose for more than 1 and half month to control & completely cure the disease.
Key words: EM, Encrustations, Mucocutaneous, Plaques, Erosions
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