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Review Article

SRP. 2018; 9(1): 64-69


Active Compounds and Antimalaria Properties of some Medicinal Plants in Indonesia – A Review

Maulana Yusuf Alkandahri, Afiat Berbudi, Anas Subarnas.


Abstract

Indonesia is a tropical country rich with various types of plant that have
been empirically used as alternative medicine, especially for malaria disease
treatment. The discovery and development of malaria treatment are
currently underway, given that there has been a lot of resistance to firstline
malaria treatment. The case of resistance has spread around the world
that cause many victims, including in Indonesia. With Indonesia has a good
environment for the development of malaria disease, therefore it requires
serious treatments to prevent the spreading of malaria. Several efforts
have been made to reduce the death cases due to malaria in Indonesia, including
the discovery of new compounds from nature that has antimalarial
compound as a substitute for malaria’s drugs that is known has resistance.
Research for a new antimalarial compound from nature is based on the
experience of Indonesian ancestors who usually used various plants to
treat many kinds of disease. Furthermore, research for natural compound
especially from Indonesia that has the potency as alternative treatment for
malaria is expected to continue to be developed. Some types of plant, such
as puspa leaves (Schima wallichii Korth), sernai leaves (Wedelia biflora),
kembang bulan leaves (Tithonia diversifolia), bark of cempedak (Artocarpus
champeden), and sambiloto leaves (Andrographis paniculata Nees) have
long been used as alternative herbal treatments for malaria in various regions
in Indonesia. These plants have been proven empirically efficacious
as antimalarial medicine, and several studies haves been conducted on
these plants to obtain active compounds that have antimalarial property.

Key words: Antimalaria, Schima wallichii korth, Wedelia biflora, Tithonia diversifolia ((Hemsley) A. Gray), Artocarpus champeden, Andrographis paniculata Nees.






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