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Review Article

SRP. 2019; 10(1): 15-19


A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata

Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi.

Abstract
Andrographis paniculata Nees is an annual herbaceous plant which belongs to the family Acanthaceae. It is commonly known as Kalmegh, is found in the plains of India, China, Pakistan, Sri Lanka and South Asia and is native to India and Sri Lanka. Kalmegh is known to be the “king of bitters” though it is of small size and it also has a similar appearance and taste as that of the Neem plant. It is one of the widely used effective medicinal plants
in the world. All parts of this plant are used to extract the potential
phytochemical, but the composition of phytoconstituents mostly differs
from one part to another in a season, place and time of harvest. It is a
traditional medicinal plant widely used in the treatment of anti-inflammatory,
anti-bacterial, anti-oxidant, hepatoprotective, hematocidal, anti-HIV, anti-cancer, anti-diabetic, arthritis, rheumatism, cough, cold, multiple sclerosis, depression, diarrhoea, dysentery, candida, fevers, herpes, leprosy, malaria,
jaundice, tuberculosis and several infectious diseases ranging from malaria
to dysentery. The plant is widely used in Ayurvedic and homeopathic system
of medicine. The medicinal value of this plant is due to the active ingredients
via andrographolide and neoandrographolide, which are derivative of diterpinoids. It prevents oxidative damage and inhibits binding of toxic metabolite
to DNA.

Key words: Andrographis paniculata, Anthraceae, Andrographolide, Neoandrographolide, Kalmegh.


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