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IJPRT. 2014; 4(1): 07-11

Electroporation: An Emerging Technique For Drug Delivery

Paria U*, Bhangi A..


Electroporation is an emerging field in delivery of drugs into the body by any medium or vector. Now a day, it is widely
used in many routes for the treatment of diseases. Electroporation is a process in which an electric field is applied to the
living cell which results in formation of pores in cell. In this method, viruses or plasmids enter into the cell in the form of
vector. For this method instruments like Eppendorf Eporator are used to provide a fast, simple and safe path to administer
bacteria, yeast or any other micro-organism as a vector inside the body with DNA/RNA. This technique offers a large
number of applications in various fields such as DNA transformation, induced cell diffusion, in transdermal drug delivery,
chemotherapy, gene therapy etc. This review deals with the applications, recent developments future scenario of this process.
Electroporation knife is the latest invention used to kill the cancer tumors. Feasibility of transdermal electroporation for
insulin loaded nanocarriers is another achievement. This approach may also use in nuclear targeting. Countless researches
still going on to produce an efficient, safe and simple process for treatment of diseases and provide a better future to the
human beings.

Key words: Electroporation, Iontophoresis, Microneedle, Penetrationenhancer, Sonophoresis, Transdermal.

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