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IJPRT. 2011; 1(1): 06-11


Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits

Biren N. Shah, Khodidas D. Raiyani*, D. C. Modi.




Abstract

In the indigenous system of medicine, the fruits of Momordica charantia Linn. (Family- Cucurbitaceae) are reported to be useful in the treatment of urinary stones. Hence, in the present study the fruits of Momordica charantia Linn. have been selected for their antiurolithiatic activity on experimentally induced urolithiatic rats. Antiurolithiatic activity of fruit extract of M. charantia Linn. was carried out on ethylene glycol (0.75% v/v) induced urolithiasis in rats. Treatment with Aqueous Extract (200mg/kg, p.o) and Alcoholic Extract (250mg/kg, p.o) of fruits of M. charantia Linn. significantly lowered (P

Key words: Momordica charantia Linn., Urolithiasis, Ethylene glycol, calcium oxalate.






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