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Prevalence of anemia and its correlation with HBA1c of patients in Type-II diabetes mellitus: A pilot study

Ankeet Kumar Panda, Rakhee Ajay Ambade.




Abstract

Background: Decrease in oxygen carrying capacity of the blood due to deficient erythropoietin is the characteristic of chronic kidney disease. Furthermore, the diabetic nephropathy secondary to uncontrolled diabetes mellitus (DM) leads to anemia in patients. Many reports suggest the presence of anemia in patients with diabetes with renal insufficiency while few studies indicating the incidence of anemia in diabetic patients before renal impairment.

Aims and Objective: The aims of this study were to find out the prevalence of anemia among patients with Type 2 diabetes with and without renal insufficiency.

Materials and Methods: It is a cross-sectional study including 54 Type 2 diabetic patients in 3 months period, visiting the Department of Medicine. Hemoglobin percentage, HbA1c, and serum creatinine were found out after collecting blood. Alcoholic, smokers, patients on hematinic, and liver disease were excluded from the study. All data were analyzed using Epi-info software. Analysis was performed using chi-square test. P values < 0.05 were considered to be statistically significant.

Result: The mean age of the study population was 51.39 ± 8.8 years. The overall prevalence of anemia was found to be 67%, which includes 20 patients with renal insufficiency and 34 with normal kidney status, with 70% and 58.8% prevalence of anemia, respectively. There was no statistical significant difference between these two groups (P > 0.05). Anemia was more common in male (66.7%) compared to female (57.1%) diabetic population.

Conclusion: Poor glycemic control is related to the prevalence of anemia in patients with DM.

Key words: Diabetes Mellitus; Glycosylated Hemoglobin; Hemoglobin; Prevalence






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