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Effect of age on cardiac output after coronary angioplasty in patients of acute myocardial infarction

Samir Kumar Singh, Manish Bajpai, Sunita Tiwari, Rishi Sethi, Dileep kumar Verma, Gaurav Chaudhary.


Background: Although most of the acute coronary syndrome (ACS) patients are elderly, less data available on the effect of age on outcome after percutaneous coronary interventions (PCI) and major adverse cardiovascular events. In this study, we evaluated the effect of age on clinical outcomes in patients with ACS undergoing PCI because it is a well-known fact that the ages of patients influence clinical outcomes in ACS.

Aims and Objectives: The aim of the study was to find out the effect of age on outcome of angioplasty in acute myocardial infarction (AMI) patients.

Materials and Methods: It is a cross-sectional, self-control, interventional study. In this study, cardiac output (CO) of 52 patients of AMI was measured by echocardiography before and after angioplasty. CO is calculated with the help of end diastolic volume, end systolic volume, and left ventricular outflow tract diameter. Statistical software IBM SPSS version 16 was used for analysis of data.

Results: A negative and statistically significant coefficient of correlation (r = −0.384 and P = 0.005) was found between age of patients and the value of CO after coronary angioplasty. Linear regression analysis was also done taking CO after coronary angioplasty as dependent variable and age of the patient as the independent variable. It can be hypothesized that as the age advances, CO after angioplasty deteriorates.

Conclusion: Advancing age is associated with deterioration in outcome after coronary angioplasty in AMI patients.

Key words: Acute Myocardial Infarction; Age; Cardiac Output

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