Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

Anaesth. pain intensive care. 2018; 22(2): 165-173


“A comparative evaluation of dexmedetomidine-propofol versus fentanyl-propofol for insertion of Laryngeal Mask Airway.”

Dr. Shobhana C Gupta, Dr. Hina Niraj Gadani, Dr. Priyanka R Shah.




Abstract

Background:“Laryngeal Mask Airway” (LMA) keeps a patient’s airway open during anaesthesia. When propofol is used along with either fentanyl or dexmedetomidine, it provides stable cardiorespiratory condition, diminished airway reflexes and smooth insertion of LMA.
Aim: Aim of this study is to compare the hemodynamic and respiratory parameters and patient’s response to LMA insertion between dexmedetomidine-propofol and fentanyl-propofol combinations as a primary outcome. Secondary outcome is to observe any side effect in intraoperative and postoperative period associated with the study drugs.
Methodology: Prospective, double blind, randomized clinical study in 140 healthy patients of both sex, having ASA grade I and II was carried out. Patients were demographically similar. Patients were randomized to receive either intravenous (i.v.) dexmedetomidine(1μg/kg)–propofol(2mg/kg) injections- Group D (n = 70) or i.v. fentanyl(1μg/kg)-Propofol(2mg/kg) injections- Group F (n = 70) for LMA insertion. Parameters like heart rate(HR), respiratory rate (RR), systolic blood pressure(SBP), diastolic blood pressure(DBP),oxygen saturation(SpO2%) were recorded baseline, during LMA insertion, 1, 3, 5, 10, 15, 30 minutes (min.) after LMA insertion.Patient's response to LMA insertion such as jaw mobility, coughing/movement were noted. Other side effects were observed.
Results: Significant decrease in HR, SBP, DBP in patients of group Dthroughout the study procedure. In group-F there was rise in the above parameters noted 1st and 3rd minute after LMA insertion. The difference was statistically highly significant between the two groups throughout the procedure.(p

Key words: Injection (inj.) propofol, inj. dexmedetomidine, inj. fentanyl, laryngeal mask airway, LMA insertion






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.