Primary neuroendocrine tumors of the liver are seldom seen. This is the case report of 45 years old woman who
presented with right upper quadrant vague abdominal pain and low grade fever. On examination a firm mass
about 6 × 4 cm was palpable in left hypochondrium and epigastrium. Ultrasound and CT-scan showed mass of
left lobe (segment II and III) of liver. There was no evidence of cirrhosis and hepatitis B and C status was
negative. The tumor markers were also within normal values. Core biopsy confirmed a tumor of neuroendocrine
origin. Octreotide scan was done which confirmed that liver was the primary site of neuroendocrine tumor. Left
lobectomy (Segment II & III) was done. The diagnosis was confirmed on histopathology and immune histochemistry
Immunohistochemistry, Neuroendocrine carcinomas, Octreotide.