Abstract

Background:
The treatment of wounds associated with diabetes is among the common issues encountered in veterinary healthcare.

Aim:
This research endeavor sought to prepare and evaluate the impact of the composition of Boswellia serrata extract (BSE) and T. foenum-graecum seed extract (TFGE) on the healing of induced diabetic wounds in rats.

Methods:
Thirty-two clinically healthy adult male rats, aged 6-8 months and weighing 280 ± 20 g, were used in this study. After partial pancreatectomy, 2 equal groups (n = 16) were randomly selected among the 32 experimental animals and exposed to a full-thickness excisional wound. Group Ι, represented control, was treated with topical application of penicillin-streptomycin antibiotic, and group II was treated with ointment prepared from 20% BSE and 10% TFGE. Each group was treated daily for 21 days.

Results:
Macroscopic analysis exhibited significant superiority (P

Key words: Boswellia Serrata; Diabetic rat; Gene Expression; T. foenum-graecum seed extract; Wound healing.