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Self-estimated effect of treatment with botulinum toxin in the upper extremity of children with Cerebral Palsy (CP)

Linda Linné, Kerstin Sommerstein, Anette Chemnitz, Helena Erixon, Lars B. Dahlin.

Objectives: National Swedish guidelines for treatment with botulinum toxin in children and adolescents with cerebral palsy (CP) include evaluation of self-estimated effects of treatment. We hypothesized that the treatment effect subsides after the first injection.
Methods: Children (or their parents), receiving their first botulinum toxin treatment of upper limb before the age of 20 years, filled in a questionnaire (visual analog scale; VAS) six weeks after each injection.
Results: Eighty-one out of 95 children or adolescents were evaluated (35% girls; 65% boys; 61% unilateral; 34% bilateral; 5% dyskinetic). Patients with unilateral CP were younger (median 8, range 1-19 years) than those with bilateral CP (12.5, 4-19 years; p

Key words: Botulinum toxin type A, cerebral palsy, children, self-estimated effect, upper extremity

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American Journal of Physiology, Biochemistry and Pharmacology


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