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Study of clinical, etiological, and biochemical profile of patients with liver abscess: A prospective study

Abhay S Tirkey, Maneesh Jain.


Background: Liver abscess comprises 48% of all the visceral abscesses. Worldwide, approximately 40–50 million people are affected annually with abscesses. It is common in India with second highest incidence due to poor sanitation, overcrowding, and inadequate nutrition.

Objectives: The objective of this study is to evaluate patient with liver abscess for etiology, clinical features, and biochemical abnormality.

Materials and Methods: A total of 104 liver abscess patients diagnosed on the basis of ultrasonography were studied in the Department of Medicine, GR Medical College and J A Group of Hospital, Gwalior, from November 2009 to October 2011. All patients are subjected to detailed clinical examination and biochemical testing. On the basis of microbiological study, three groups were formed: Aamoebic liver abscess (ALA) group (n = 39), pyogenic liver abscess (PLA) (n = 28) group and not aspirated Group (n = 37).

Results: Most of the patients belong to ALA group (58.2%) with male preponderance (90.1% in ALA and 60.7% in PLA group) (P = 0.0038). Maximum number of patients of ALA were in 40 years, with comorbid condition such as diabetes or cholelithiasis or cholangitis with pulmonary finding, whereas ALA occurs in young male

Key words: Bacterial Growth; Percutaneous Aspiration; Cholelithiasis; Alkaline Phosphatases

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