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Original Research

RMJ. 2019; 44(1): 89-93


Microbiology and antibiotic susceptibility patterns of wound and soft tissue infections on surgical floor Mayo Hospital, Lahore, Pakistan

Balakh Sher Zaman, Salman Farooq Dar, Malik Muhammad Atif, Talha Farooq Dar.

Abstract
Objective: To determine frequency of different organisms from wound, skin and soft tissue infection and determine their resistance and sensitivity pattern.
Methodology: This retrospective descriptive study was done by analyzing data from records of Microbiology laboratory, Pathology Department, King Edward Medical University Lahore, Pakistan.
Results: Among 231 isolates, Pseudomonas was the most common organism; 80/231 (34.6%), followed be Staphylococcus aureus; 52/231 (22.5%) and E. coli 47/231 (20.3%). For gram-positive organisms, Linezolid was the most active drug (sensitivity 96.88%) followed by Vancomycin (sensitivity 95.74%). For gram-negative organisms, Teicoplanin was the most active drug (sensitivity 96.15%), followed by Piperacillin+Tazobactam (sensitivity 94.31%), Imipenem+cilastin (sensitivity 78.95%) and Meropenem (sensitivity 78.72%).
Conclusion: Most common isolates were resistant to most of the first line agents while some effective alternatives still exist.

Key words: Wound and Soft tissue infections, antibiotic resistance, empirical therapy, Pseudomonas, Carbapenems



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