Objective: Sickle cell anemia (SCA) is one of the leading causes of child morbidity and mortality in Nigeria. About 25 % of the country’s population are carriers of the mutant gene responsible for the disease. Free radicals promote irreversible sickling of red blood cells (RBC) and damage its membrane. This study was designed to evaluate the effect of camel milk administration on oxidative stress biomarkers in sickle cell anemia patients.
Methods: 45 children aged 5 - 15 years old were recruited for the study. The patients were randomly divided into 3 groups, (i) HbAA: control group administered with 10 ml/kg of camel milk, (ii) HbSS-1: SCA subject administered with routine SCA drugs, (iii) HbSS-2: SCA administered with SCA drugs plus 10 ml/kg of camel milk.
Results: It was observed that three weeks of camel milk administration had resulted in significant changes in oxidative stress biomarkers. Serum level of GSH, vitamin C and E were significantly increased (P
Camel milk, Sickle cell anemia, antioxidants, Oxidative stress.