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Original Research

RMJ. 2019; 44(3): 509-512


Efficacy of corticosteroids in acute bronchiolitis: short term outcomes

Shaheen Ahmad, Sohail Shahzad, Umar Nawaz Khan, Muhammad Ahsan Shahzad, Mohid Ahmad, Maheen Ahmad.

Abstract
Objective: To determine short term efficacy of corticosteroids, when added to beta 2 agonist, in acute bronchiolitis.
Methodology: This randomized controlled trial was conducted at pediatric department in Combined Military Hospital, Abbottabad, Pakistan from January to June 2018. A sample size of 80 patients was calculated using WHO calculator. Non probability consecutive sampling was used. Patients were randomly divided into two groups; Group A was given oral prednisone for 3 days while group B placebo. All were followed after 7 days. SPSS version 24 was used for data analysis. Chi-square test was applied. P≤0.05 was considered significant.
Results: Out of 80 infants, there were 44 (55%) male and 36(45%) female. Mean age was 11.4±1.5 months. Corticosteroids showed significant reduction in respiratory rate (p=0.02), oxygen saturation SpO2(p=0.001), length of hospital stay (p

Key words: Corticosteroids, acute brochiolitis, prednisone.



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