Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



Case–control study evaluating relationship of blood pressure and anthropometric parameters with non-alcoholic fatty liver disease

Wilson S Joseph, Nirmal George, Abhaya Prasannarajan, Abhilash Kannan.

Abstract
Background: The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased over the last decade. India is one of the countries with highest prevalenceof NAFLD. High prevalence of lifestyle disorders among Keralites and their association with NAFLD necessitates studies on the subject.

Aims and Objective: Owing to the scarcity of studies evaluating the association of NAFLD with anthropometric and clinical parameters in Kerala, the present study was conducted.

Materials and Methods: Our case–control study enrolled 81 cases (with NAFLD) and 79 controls (without NAFLD) who were undergoing voluntary health checkup over a period of 2 years. Institutional Ethics Committee approved the study and written informed consent was obtained from all the study participants. Sociodemographic, anthropometric parameters and blood pressure (BP) were recorded and categorized based on gender, body mass index (BMI), and BP (JNC-8). Data were analyzed using free software R™. Independent sample t-test, Mann–Whitney U-test, and Chi-square test were used for statistical analysis and P < 0.05 was considered statistically significant.

Results: 15% and 11% of the study participants were having normal BMI and BP, respectively. Cases were significantly taller (P = 0.003), were having higher BMI (P = 0.04), weight (P < 0.001), waist circumference (WC) (P = 0.02), and systolic BP (SBP) (P = 0.02) compared to controls.Significant association was observed between NAFLD and stage 2 hypertension (P = 0.04). Our study did not demonstrate any association between NAFLD and BMI (P = 0.2) and between NAFLD and WC (P = 0.7).

Conclusion: High prevalence of weight-related and BP disorders were seen in participants undergoing voluntary health checkup. NAFLD was associated with a significantly higher weight, BMI, height, SBP, and WC. Significantly higher odds of NAFLD were seen in participants with Stage 2 hypertension.

Key words: Non-alcoholic Fatty Liver Disease; Stage 2 Hypertension; Weight-Related Disorders; Lifestyle Disorders; Pre-hypertension



Share this Article


Advertisement
Journal of Apitherapy

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.