The effect of chemical restraints with either 2.0mg/kg intramuscular injection of xylazine hydrochloride or 0.1mg/kg intramuscular injection of acepromazine during standard excretory urography was studied in five adult local dogs receiving 800mgI/kg intravenous injection of 76% Urograffin®. Radiographs were obtained immediately, at 10 mins, 20 mins and 40 mins post injection of Urograffin, while scores ranging from 1-4 was assigned to nephrographic densities. Also, respiratory rates (RR), heart rates (HR) and pulse rates (PR) were determined before sedation, after sedation, immediately after contrast agent administration and at 10 minutes interval during the 40 minutes duration of urography. In addition, adverse effects associated with injection of the drugs were noted as at when they occurred. In this study, sedation with xylazine was associated with few adverse effects such as transient apnoea and arrhythmia. Nephrographic opacification score was significantly (P
Key words: Ajadi Rasheed Adetola, Adetunji Adeniran, Adeniyi Abisola Abosede
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