Psychotropic-induced hyponatremia, is the commonest electrolyte imbalance experienced in the psychiatric practices. It is commonly seen in geriatric patients and it is always overlooked and untreated in psychiatric patients, and that would explain why it leads to increased mortality. Psychotropic drugs such as, antidepressants, antipsychotics, mood stabilizers, and sedative-hypnotics can lead to hyponatremia, however it commonly occurs in antidepressant. In this review, a thorough internet search was done using the search engines of ResearchGate, PubMed, Scopus, PsycInfo, ScienceDirect, and Google Scholar. Present review sheds light on the probable psycho-pathology, evaluation of hyponatremia, a closer look at its different types of hyponatremia, its incidence with various psychotropic medications. We will also summarizes the clinical presentations of hyponatremia, the identified risk factors with various psychotropic, and will conclude by discussing the mainstay management of hyponatremia.
Key words: Hyponatremia, low serum sodium, selective serotonin reuptake inhibitors, syndrome of inappropriate secretion of antidiuretic hormone.
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