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Original Research

RMJ. 2021; 46(3): 745-748


Effect of Ficus carica on lead acetate induced changes in diameter of seminiferous tubules of adult rat testis

Ayesha Asad, Shabnam Hamid, Saima Qureshi.




Abstract

Objective: To assess the effect of Ficus carica on lead acetate induced changes in diameter of seminiferous tubules in testis of adult rats.
Methodology: Thirty healthy adult male Sprague-dawley rats were selected and divided into three groups; each consisting of 10 animals. Group A served as control. Group B was given lead acetate 30 mg/kg bodyweight/day. Group C received Ficus carica 80 mg/ kg bodyweight/day in addition to lead acetate 30 mg/kg bodyweight/ day. The dose was administered once a day for a period of 8 weeks. Twenty-four hours after administration of last dose, the animals were sacrificed and testes were removed. Testicular tissue was processed and stained with hematoxylin and eosin. Diameter of seminiferous tubules was measured. The data were analyzed using SPSS version 22. Results were considered significant at p

Key words: Diameter, Ficus carica, seminiferous tubules, rats.






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