Home|Journals|Articles by Year|Audio Abstracts

Original Article

The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function

Nagi I Ali, Abdullah O Alamoudi, Yousif Mohamed Y Abdullah.


In this study, forty-nine – under five years, male & female Sudanese children, presented with protein energy malnutrition (PEM, Kwash) according to the WHO criteria have been studied for their thyroid function and other biochemical Parameters. Triiodothyronine (T3), Thyroxine (T4) and Thyroid Stimulating Hormone (TSH), as a thyroid function indicators, the study included determination of Thyroglobulin (TG), Ferritin, Protein Moreover, Hemoglobin levels in serum. The study was done in different hospitals in Khartoum state. Patients being assessed & examined by pediatricians using a unified clinical protocol and a questionnaire for patient’s characteristics. Thyroid hormones and Ferritin were measured by a sensitive radioimmunoassay (RIA) Technique in 49 children with malnutrition as well as a control group of 20 healthy children. When the results of malnourished children compared to normal children showed that; 22% of malnourished children have severe hypothyroidism (T4 < 30 mol/l) and (T3 < 0.5 mol/l) as the reference range (50 – 150mol/l) and (0.8 – 3 mol/l) respectively. The mean level of TSH for patients was within the normal range but it was lower than the mean of TSH levels for controls. The mean values of TG and Ferritin for patients was higher than that of controls. Protein and Hemoglobin values showed low levels in Patients and negative clinical correlation between Ferritin and Hemoglobin has been found. Our conclusion of this study states that, malnutrition has severe effects on thyroid function.

Key words: Nuclear Medicine, Thyroid Function

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.