Home|Journals|Articles by Year|Audio Abstracts
 

Original Research



The relationship between helicobacter pylori infection and gastric cancer

Aziz Ari, Kenan Buyukasik.




Abstract

Immediately after Helicobacter pylori (H. pylori) was discovered in 1983, its relationship with upper gastrointestinal diseases has begun to be investigated. This study was carried out to investigate the relationship between H. pylori and gastric cancer by comparing the frequency of H. pylori infection between gastric cancer patients and controls. Histological results were evaluated in the diagnosis of H. pylori. This study included 60 patients who were diagnosed as gastric cancer at the Endoscopy Unit of Education and Research Hospital and were operated at the General Surgery Department of Istanbul Education and Research Hospital. The patients were questioned about major complaints and duration of these complaints, cigarette smoking and tea drinking habits, family history, and previous gastrointestinal surgery. The localization, macroscopic appearance, histology, and extent of the tumor were determined. Endoscopy, biopsy and tomography examinations were used for the localization, shape and spread of the tumor in other patients. In 40 patients undergoing resection, histological presence of H. pylori in tumor-adjacent tissue was detected in 28 (70%) patients. When all patients (60 patients) were evaluated together, H. pylori infection was detected in 40 (66.7%) patients. 40 patients undergoing resection were included in the evaluation. Although the frequency of H. pylori infection was higher in diffuse-type than in intestinal-type, this was not statistically significant. Both patients with intestinal and diffuse gastric cancers were accompanied by H.pylori infection. The rate of H.pylori infection was higher in patients with diffuse gastric cancer. Although H. pylori is one of the etiologic factors for gastric cancer, there was no significant difference in H. pylori infection between those with and without gastric cancer.

Key words: Cancer, gastric, helicobacter pylori






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.