Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Article

Majmaah J Heal Sci. 2015; 3(1): 28-32

The high Percentages of Anti-thyroid Antibodies Positive SLE Patients at Sheikh Zayed Hospital, Lahore (Pakistan)

Muqaddas Riaz, Nadeem Afzal, Tafazzul H Mahmud, Faheem Shahzad, Sabrina Rasheed, Aflak Rasheed.

BACKGROUND & OBJECTIVES: Systemic lupus erythmatosus (SLE) is an autoimmune disease and more than 100 auto antibodies have been detected in SLE. The present study was designed to determine the presence of anti-thyroid antibodies (ATA) in SLE patients.

METHODS: It was a descriptive study and 42-SLE patients positive for anti-nuclear antibodies (ANA) and or anti-ds DNA (ds-DNA) antibodies were selected from Department of Rheumatology, Sheikh Zayed Hospital Lahore. Blood sample was collected and ATA was determined by indirect immunofluorescence technique.

RESULTS: Thirty-nine (39) (92.9%) and 32 (76.2%) patients had ANA and ds-DNA antibodies respectively. On comparison, it was not statistically significant. Twenty- three (23) (54.76%) subjects had ATA and on comparison, it was not statistically significant. All the positive patients for ATA were females.

CONCLUSION: Sensitivity of ANA and ds-DNA positive suspected SLE subjects to have ATA in their serum was 74%. About 55% of SLE patients were positive for ATA.

Key words: Systemic lupus erythematosus, Anti-thyroid antibodies, Immunofluorescence

Similar Articles

Clinical Performance of Two Automated Immunoassays, EliA CTD Screen and QUANTA Flash CTD Screen Plus, for Antinuclear Antibody Screening.
Yoon S, Moon HW, Kim H, Hur M, Yun YM
Annals of laboratory medicine. 2022; 42(1): 63-70

Cell Free Remodeling of Glycosylation of Antibodies.
Mota LM, Tayi VS, Butler M
Methods in molecular biology (Clifton, N.J.). 2022; 2370(): 117-146

Comparison of the Automated Fluorescent Immunoassay System With Roche Elecsys and Beckman Coulter Access 2 Assays for Anti-Müllerian Hormone Measurement.
Han A, Suh B, Yi G, Lee YJ, Kim SE
Annals of laboratory medicine. 2022; 42(1): 47-53

Hormone Immunoassay Interference: A 2021 Update.
Ghazal K, Brabant S, Prie D, Piketty ML
Annals of laboratory medicine. 2022; 42(1): 3-23

Role of HSPGs in Systemic Bacterial Infections.
Aquino RS, Hayashida K, Hayashida A, Park PW
Methods in molecular biology (Clifton, N.J.). 2022; 2303(): 605-625

Full-text options

Latest Statistics about COVID-19
• pubstat.org

Add your Article(s) to Indexes
• citeindex.org

Covid-19 Trends and Statistics
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.

ScopeMed Web Sites