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Level of serum prolactin in patients of hypothyroidism in Western Uttar Pradesh

Jaskiran Kaur, Akash Gupta, Mushir Ahmad, Prasanna Chandra M.


Background: Hypothyroidism refers to a state that results in a deficiency of thyroid hormones, including hypothalamic or pituitary disease and generalized tissue resistant to thyroid hormone. Thyroid-releasing hormone can cause a rise in serum prolactin levels in patients of primary hypothyroidism.

Objective: The objective of the study was to find the levels of serum prolactin in patients who are having hypothyroidism and to observe the relationship of prolactin with thyroid-stimulating hormone.

Materials and Methods: A total of 150 patients coming to endocrinology clinic for thyroid-related problems were selected for the study and analyzed for their serum T3, T4, thyroid-stimulating hormone (TSH), and prolactin levels by enzyme-linked fluorescent assay technique using Vidas autoanalyzer from Biomeriuex, France.

Results: Prolactin level is high in the subclinical hypothyroid patients and hypothyroid patients as compared to euthyroid patients.

Conclusion: In our study, it was seen that the levels of prolactin rise in relation to rising TSH level in hypothyroid patients.

Key words: Prolactin, Hypothyroidism, T3, T4, Thyroid-stimulating Hormone

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