Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Article

PAFMJ. 2017; 67(6): 1003-1007


FREQUENCY OF RHEUMATOID FACTOR IN PATIENTS WITH HEPATITIS C INFECTION ASSOCIATED POLYARTHROPATHY

Tahir Mukhtar Sayed, Ghulam Hussain Ibrahim, Muhammad Rashid Ahmed, Muhammad Umer Siddiqui, Imtiaz Ali.

Abstract
Objective: To determine the frequency of Rheumatoid Factor (RF) in patients with Hepatitis C infection (HCV)
associated polyarthropathy at Combined Military Hospital Quetta.
Study Design: Cross-sectional study.
Place and Duration of Study: Department of Medicine, Combined Military Hospital Quetta, from 1st Oct 2012 to
31st Mar 2013.
Material and Methods: Two hundred and seven patients having confirmed Hepatitis C infection (positive anti
HCV antibodies and positive HCV RNA by Qualitative PCR) with polyarthropathy were included in this study.
These patients were screened for RF by immunonochromatography based RF Latex assay kit.
Results: Out of 207 patients, 138 (66.67%) were males and 69 (33.33%) were females. The age among all subjects
ranged from 2155 years and mean age of all subjects was 44.29 4.61 years, the youngest patient was 21 years
old and eldest was 55 years old. Most of the patients 97 (47%) were in the age group of 36-45 years. RF was
positive in 88 (42.51%) patients and it was negative in 119 (57.49%) patients suffering from hepatitis C infection
associated polyarthropathy. The frequency of RF in female patients was 66 (48%) and in male patients was 22
(32%) and it was significantly (p-value=0.0367) greater in female patients as compared to male patients.
Conclusion: The detection of Rheumatoid Factor (RF) is of little utility as a diagnostic tool for concurrent RA in
patients of chronic HCV infection because a high percentage of them were having serum RF reactivity.

Key words: Arthropathy, Hepatitis C, Rheumatoid factor.



Share this Article


Advertisement
Journal of Molecular Pathophysiology

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.