Home|Journals|Articles by Year|Audio Abstracts

Original Research

Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia.


Background: Streptococcus mutans is known as primary microorganism in the formation of dental plaque and tooth decay.

Aims and Objectives: To determine the antibacterial activity of ant-nest plant ethanol extract to inhibit S. mutans clinical isolates growth in vitro.

Materials and Methods: The ethanol extracts obtained from the ant-nest plant were studied for antibacterial activity against cariogenic S. mutans obtained from patients with clinically identified carious lesions, using the agar diffusion method. Chlorhexidine gluconate was using as a comparative drug. The simplisia of ant-nest plant was extracted using a maceration method. The phytochemical screening was taken using standard methods. The minimum inhibitory concentration (MIC) test was performed by a macrodilution method and following by subculturing the overnight result onto the surface of agar media.

Results: Phytochemical screening of ant-nest plant ethanol extract revealed the presence of polyphenols, flavonoids, tannins, and saponins. The extract showed intensive activity and totally inhibited the growth of S. mutans clinical isolates at 1.25% w/v. In comparison, the chlorhexidine gluconate, essential oil of plants and povidone-iodine in a ranged tested concentration also had given inhibition effect to all hyaluronic acid resistant S. mutans isolates.

Conclusion: It can be reasoned that the ethanolic extract of ant-nest plant gave potent and direct antibacterial effect on S. mutans.

Key words: Ant Nest; Antibacterial; Streptococcus mutans; Caries; Hyaluronic Acid

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.