Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Case Report

Pak J Nucl Med. 2013; 3(1): 73-77


Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah.

Abstract
Medullary thyroid carcinoma (MTC) is a distinct C-cell tumour of the thyroid gland that produces calcitonin in high quantities. Various imaging techniques are available in nuclear medicine to image MTC which include 131I-MIBG and somatostatin receptor imaging agent 111In-Octreotide.Due to the nonavailability of these agents in Pakistan, we tried using locally prepared 99mTc-labelled pentavalent dimercaptosuccinic acid (99mTc(V)-DMSA) in a patient suspected of advanced MTC. CT with contrast could not be performed in this patient due to raised serum urea and creatinine levels indicating renal impairment. 99mTc(V)-DMSA was prepared by modification of a locally formulated kit of renal DMSA. Significant accumulation of the tracer was seen in the gross disease present in the neck and mediastinum. The resolution and good physical characteristics of 99mTc(V)-DMSA make it a useful agent for MTC imaging, where other modalities are not available.


Full-text options

Full-text Article




Advertisement
Journal of Complementary Medicine Research

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.