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Letter to the Editor

Sudan J Paed. 2017; 17(2): 71-73


Burosumab - a new drug to treat hypophosphatemic rickets

Stepan Kutilek, Amir Babiker, Badi Alenazi.




Abstract

Burosumab (KRN23) is a fully human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets. A report enclosed in this letter gives a brief review of current knowledge on burosumab therapy.

Key words: Burosumab, Hypophosphatemic rickets, KRN23






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